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ByteDance Seed·Dec 30, 2025·v1.0·open source

SeedFold

SeedFold is an advanced biomolecular structure prediction model developed by ByteDance Seed. It enhances the capacity of folding models through width scaling and large-scale data distillation, achieving state-of-the-art results on FoldBench and outperforming AlphaFold3 on most protein-related tasks.

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overview

SeedFold is an advanced biomolecular structure prediction model developed by ByteDance Seed. It enhances the capacity of folding models through width scaling and large-scale data distillation, achieving state-of-the-art results on FoldBench and outperforming AlphaFold3 on most protein-related tasks.

key features
  • 01Width scaling of Pairformer module to 512 dimensions
  • 02Introduction of linear triangular attention reducing computational complexity
  • 03Construction of a 26.5 million sample distillation dataset from AlphaFold2
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